Temporal Difference Error Prediction Signal Dysregulation in Cocaine Dependence
نویسندگان
چکیده
منابع مشابه
Polysomnographic sleep dysregulation in cocaine dependence.
Insomnia and sleep disturbance are associated with declines in health functioning, along with increases in mortality risk. Given the prominence of reported sleep disturbance in cocaine-dependent subjects and persistence into recovery, understanding the nature and severity of these disturbances in this population may help to identify relevant pathways that contribute to the increased mortality i...
متن کاملAn Imperfect Dopaminergic Error Signal Can Drive Temporal-Difference Learning
An open problem in the field of computational neuroscience is how to link synaptic plasticity to system-level learning. A promising framework in this context is temporal-difference (TD) learning. Experimental evidence that supports the hypothesis that the mammalian brain performs temporal-difference learning includes the resemblance of the phasic activity of the midbrain dopaminergic neurons to...
متن کاملError-related functional connectivity of the thalamus in cocaine dependence
Error processing is a critical component of cognitive control, an executive function that has been widely implicated in substance misuse. In previous studies we showed that error related activations of the thalamus predicted relapse to drug use in cocaine addicted individuals (Luo et al., 2013). Here, we investigated whether the error-related functional connectivity of the thalamus is altered i...
متن کاملIncremental Basis Construction from Temporal Difference Error
In many reinforcement learning (RL) systems, the value function is approximated as a linear combination of a fixed set of basis functions. Performance can be improved by adding to this set. Previous approaches construct a series of basis functions that in sufficient number can eventually represent the value function. In contrast, we show that there is a single, ideal basis function, which can d...
متن کاملShifting Attention Using a Temporal Difference Prediction Error and High-Dimensional Input
Research on reinforcement learning has increasingly focused on the role of neuromodulatory systems implicated in associative learning. Formulations of temporal difference (TD) learning have gained a great deal of attention due to the similarity of the TD prediction error and the observed activity of dopamine neurons in the primate midbrain. Recent work has attempted to integrate additional neur...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2014
ISSN: 0893-133X,1740-634X
DOI: 10.1038/npp.2014.21